One of the possible mechanisms of spread is a hematogeneous pathway, through rich anterior pituitary portal system into cavernous and petrosal sinuses, followed by jugular vein and with venous return to the lungs.[5] Nevertheless, pulmonary sites for the metastases of PCs are rarely seen.[4] For reasons still unclear, liver metastases of PC are most common.[15] Hematogenous dissemination has been reported only in a few cases, primarily of ACTH-producing carcinomas.[12] Our case is one of the rarest cases of hematogenously disseminated null-cell PC. The gene discussed is POMC; the disease is pachyonychia congenita.