SPP1 is one of the most conspicuous melanoma biomarkers [198], [199], [200], [201], [202], [203], [204], [205], [206], [207], [208], [209], [210], [211], [212], [213], [214], [215], [216], [217], [218], [219], [220], [221], [222] (see also the references cited in Figure 6 and note its eminent position in this scatter plot). The gene discussed is SPP1; the disease is melanoma.