In harmony with the data presented here in the IRAS study involving a large cohort, the authors also concluded that the ALT, another liver disease biomarker was independently associated with insulin resistance.[3] These findings are in concordance with the British Women's Heart and Health Study that observed more than a doubling in the risk of incident diabetes in ultrasonography-diagnosed NAFLD and also with the recent French data from the DESIR study that proved that individuals with a BMI of <27 kg/m2 gGT is the strongest predictor of diabetes after fasting hyperglycemia. This evidence concerns the gene GPT and metabolic dysfunction-associated steatotic liver disease.