INS and Insulin resistance: Taken this information together with our observation that NAFLD patients with normal glucose tolerance have similar HOMA2-IR values than those with type 2 diabetes, but without liver disease we would rather interpret this phenomenon as a balanced insulin resistant state, in which the higher insulin secretion and better Beta cell function in NAFLD patients overcomes the already increased insulin resistance compared to the T2D group where a significant B-cell dysfunction could be detected.