INS and diabetes mellitus: Among natural compounds, taurine (TAU) is among those most extensively investigated for its attenuating effects on diabetes-related alterations such as decreased insulin secretion [19,20], hyperglycemia [19,21] hyperlipidemia [21,22], lipid peroxidation (LPO) [21-23], and formation of advanced protein glycation products [23] in animal models of spontaneous and pharmacologically-induced diabetes.