GHRL and Sepsis: In general, ghrelin's effects are antiinflammatory and immune-enhancing, for example, diminution of monocytic, bacterial and endothelial inflammatory factors driven by endotoxin exposure, sepsis, arthritis, interleukin 1 and 6, tumor necrosis factor-alpha, and nuclear-factor kappa B [200, 577–579], and stimulation of proliferation of thymic epithelial cells and T lymphocytes [580, 581].