Enzastaurin- or Enz/EGF-treated cells displayed a significantly reduced migration and invasion as compared to DMSO- and EGF-stimulated control cells; respectively (P<0.02; Figure 1D), showing that Enz inhibits EGF-induced cell migration and invasion in addition to spontaneous invasion in NSCLC. The gene discussed is EGF; the disease is non-small cell lung carcinoma.