BSG and neoplasm: Previous studies have shown that CD147 knockdown using siRNA (Wang et al, 2006) or antibodies (Xu et al, 2007; Dean et al, 2009) inhibits tumour growth in vitro or in vivo, associated with changes in the regulation of MMP production (Xu et al, 2007, Dean et al, 2009) and radiation sensitivity of the tumours (Dean et al, 2009).