In our analysis, we compared aCGH profiles from human BRCA1/2-mutated and sporadic breast cancers with profiles from mouse p53Δ/Δ, Brca1Δ/Δ;p53Δ/Δ and Brca2Δ/Δ;p53Δ/Δ mammary tumors. This evidence concerns the gene BRCA1 and breast carcinoma.