In our analysis, we compared aCGH profiles from human BRCA1/2-mutated and sporadic breast cancers with profiles from mouse p53Δ/Δ, Brca1Δ/Δ;p53Δ/Δ and Brca2Δ/Δ;p53Δ/Δ mammary tumors. The gene discussed is BRCA1; the disease is breast cancer.