AURKA and neoplasm: Note, however, that the Aurka gain also occurred in mouse Brca1Δ/Δ;p53Δ/Δ tumors and that loss of mouse chromosomes 8 and 11 was not specific for the Brca1Δ/Δ;p53Δ/Δ tumors, suggesting that BRCA2 association of the syntenic gain and BRCA1 association of the syntenic losses are dictated by the human tumor data.