Some inherited thrombophilia defects, for instance, prothrombotic polymorphisms, Factor V G1691A, Factor II G2021A and the homozygous TT genotype of the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism, can also increase risk of neonatal arterial thrombosis [10]. Here, MTHFR is linked to Rare hereditary thrombophilia.