RBM3 and neoplasm: Multivariate analysis controlling for age, disease stage, differentiation grade and residual tumor volume (Table 2) confirmed that RBM3 expression was an independent predictor of RFS (HR = 0.61, 95% CI = 0.44-0.84, p = 0.003) and OS (HR = 0.62, 95% CI = 0.41-0.95; p = 0.028).