TEK and hepatocellular carcinoma: Tie2 was significantly up-regulated around HCC after 20W (p < 0,01), 25W (p < 0,001) and 30W (p < 0,01) compared to non-HCC tissue, and inside HCC after 25W (p < 0,001) and 30W DEN (p < 0,01 (figure 7, table 1).