The most prominent cytokines that have also been shown to be linked with cancer development were IL-6 [27,46], IL-8 (CXCL8) [47,48], GRO/GRO-α (CXCL1) [49,50], GCP-2 (CXCL6) [51], and TIMP-1 [52,53]. This evidence concerns the gene CXCL1 and cancer.