In conclusion, the A/J mice, which are more resistant to infection, displayed a better proliferative response and greater production of IL-10 and IFN-γ against CE antigen and ConA when immunized with L. minor antigens, compared to the susceptible B10.A mice which presented a lower proliferative response and less IL-10 and IFN-γ. The gene discussed is IL10; the disease is infection.