Examples include: 1) GSTP1*A is responsible for acquired resistance to cisplatin treatment due to creation of platinum-GSH conjugates [48], 2) GSTP1*B, which in certain circumstances, is associated with an impaired ability to detoxify platinum based therapeutic treatment [49], and 3) patients testing positive for GSTP1*C appear to experience breast cancer with less frequency [50]. This evidence concerns the gene GSTP1 and breast carcinoma.