IGFBP3 and diabetes mellitus: As shown, inversely correlated with serum IGF-I were age (P=0.03), alcohol intake (P=0.04), and having diabetes (P=0.03), whereas body weight and IGFBP-3 were positively associated with IGF-I levels (P<0.01), with IGFBP-3 and IGF-I having a moderately high correlation of r=0.69.