Together, these data show that CD11b+Ly6C+ monocyte recruitment to the liver of T. brucei parasite infected mice involved an egression step from the bone marrow that is CCR2-dependent, followed by a CCR2-independent extravasation step triggered by yet unidentified factors released by the inflamed tissue, as documented during bacterial infection [22], [26]. This evidence concerns the gene CCR2 and bacterial infectious disease.