On the other hand, a more pro-pathogenic function for recruited CD11b+Ly6C+ monocytic cells/Tip-DCs is supported by the observation that in CCR2 KO mice (this study) or in T. brucei infected mice treated with IL-10 [8], reduced percentage of recruited CD11b+Ly6C+ monocytic cells/Tip-DCs associated with reduced pathogenicity and increased survival without affecting parasitemia. The gene discussed is CCR2; the disease is parasitic infectious disease.