Although up to 52±4% of WT CD11b+Ly6C+ monocytic cells co-expressed CD11c and MHC-II after transfer, reflecting their differentiation and maturation towards Tip-DCs, TNF and ALT levels in recipient CCR2 KO mice did not reach levels achieved in infected WT mice at the same time point post infection (Figure 6). The gene discussed is ITGAM; the disease is infection.