The increased suppressive potency for Foxp3+ Treg at early time points after Salmonella infection we demonstrate here is consistent with the increased suppressive potency for CD25+CD4+ cells isolated day 5 after Plasmodium yoelii and day 10 after HSV-1 infection, as well as CD25+CD4+ cells isolated in the acute (day 12) and chronic phase (day 28) after Heligmosomoides polygyrus infection [14], [66], [67]. The gene discussed is CD4; the disease is Salmonella Infections.