No difference in nuclear p53 accumulation were observed between pure ADH (14/77) and ADH/DCIS (9/29) (18.2% vs. 31.0%, P > 0.05) or ADH/IDC (8/30) (18.2% vs. 26.7%, P > 0.05). Here, TP53 is linked to ductal breast carcinoma in situ.