IL-12 and IL-7 were utilized in the induction phase of the tumor-specific T cell response in vitro, because of the known function of IL-12 in directing the acquisition of strongly anti-tumor Th1/Tc1 effector functions, and of IL-7 in supporting the growth of human CD8+ T cells [29], [30], [31]. The gene discussed is CD8A; the disease is neoplasm.