ADGRL3 and non-small cell lung carcinoma: CL3 TCR+CD8+ cells killed in a MHC class I-restricted manner CaPo 13 cells also in classic 4 h 51Cr-release assays (Figure 6D), confirming that the CL3 TCR transfer endowed these allogeneic T cells with actual NSCLC-specific killer effector functions.