ARG2 was statistically significantly less expressed in tumor tissues compared to normal (p<0.001, Mann-U), to non-malignant normal adjacent (p<0.01, Mann-U) and to prostate intraepithelial neoplasia (PIN) tissues (p<0.001, Mann-U) (Figure 1D). Here, ARG2 is linked to prostate intraepithelial neoplasia.