Similarly, the majority (≥90%) of CD8+ T cells elicited by HKNPN3A infection bound the DbNP366 tetramer and produced IFN-γ (data not shown) at levels equivalent to those seen for the response to NPN3A, indicating a high level of cross-reactivity between the DbNP366+CD8+ and NPN3A+CD8+ T cell responses. Here, CD8A is linked to infection.