CD8A and infection: It was immediately apparent that the splenic DbNPN3A+CD8+ set elicited by the HKNPN3A challenge was significantly smaller on d10 (p<0.05) than the DbNP366+CD8+ T cell response induced by the wt virus (Fig 2B), though there was no significant difference between DbNPN3A+CD8+ and DbNP366+CD8+ T cell numbers at the site of infection (BAL, Fig 2A).