For example, the deletion of the chromosome 16, the 19q13.2–19q13.43 regions, and the chromosome 21 are significantly correlated with underexpression of candidate cancer-suppressor genes, respectively CBFB [37], [38] or CDH11 [39], TFPT [40] and DSCR1 [35], giving additional evidence in support of these events. The gene discussed is RCAN1; the disease is cancer.