We discovered a significantly positive correlation between eotaxin-1 in EBC and serum ECP or blood eosinophil count in the groups of patients with unstable ICS-treated asthma and steroid-naïve asthma and between eotaxin-1 and serum ECP in the group of ICS-treated stable asthma (Figure 3, Figure 4). Here, RNASE3 is linked to asthma.