The expression of CSE1L was correlated with advanced stages of melanomas and clinical stages according to the UICC which showed an increase from 43% ± 34% of CSE1L in stage I, to 53% ± 26% in stage II, 68% ± 24% in stage III, and 72% ± 24% in stage IV [7]. This evidence concerns the gene CSE1L and melanoma.