Overall in the study population, no significant differences were detected in the prevalences of hypertension, T2DM, family history of CAD, smoking, and average values of BMI, FBS, insulin, TC, LDL-C, and homeostasis model assessment of insulin resistance (HOMA-IR) among 3 groups according to 3 different genotypes at 4 SNPs in KCNQ1 (all P > 0.05). This evidence concerns the gene KCNQ1 and type 2 diabetes mellitus.