Since accumulating evidence [13], [14], [15], [16] has demonstrated that adiponectin may modulate macrophage functions, and since macrophages are involved in regulating tumor growth and progression, we decided to examine the degree of macrophage infiltration by immunohistochemical staining with the anti-F4/80 antibody, which recognizes a specific macrophage antigen. The gene discussed is ADIPOQ; the disease is neoplasm.