Furthermore, IHC-PTK6 (P=0.018, inverse), tumour size (P=0.01), and lymph node status (P=0.004) were also significant in univariate analysis, whereas no significance level was reached by IHC-HER2 (P=0.35), ER (P=0.9), and PrR (P=0.36). This evidence concerns the gene ERBB2 and neoplasm.