GRIA1 and Anxiety: We assayed GluA1 KO mice for locomotor responses to novelty andstress in an open field and behavioral responses to novel and repeated forced swim.Because the manic component is also associated with increased self-esteem,risk-taking and novelty-seeking, we tested the mutants for anxiety-related andnovelty-seeking behaviors in various tasks that differentially test these two drives(elevated plus- and zero-maze, light/dark emergence test, stress-inducedhyperthermia).