L3MBTL4 and breast neoplasm: Comparison of clinical features between breast tumors with and without L3MBTL4 loss (Table 1) showed that L3MBTL4 loss was associated with the presence of lymph node metastases (p = 1.02 10-2), high SBR grade (p = 1.15 10-2) and luminal B molecular subtype defined by SSP classification [23] (p = 3.10-5).