APOA5 and coronary artery disorder: All findings from these analyses were significant (P < 0.05) except that the association between the APOA5 -1131 T>C polymorphism and lower blood HDL-C under dominant model was marginally significant in CHD subjects: SMD = -0.21, 95% CI (-0.42, -0.01), P = 0.06, Pheterogeneity = 0.003 (Table 1).