The positive rates of BCL-2 in breast carcinoma histologic grade I, II, III respectively were 84.61%, 58.69%, 12.50%, the difference have stastistical significance(P < 0.01), The positive rates of BCL-2 in breast cancer histologic grades I, II, III to assume the declining trend, statistical analysis showed no significant difference (P = NS). Here, BCL2 is linked to breast carcinoma.