S100A7 and cancer: Based on our data, the additional prognostic value that nuclear S100A7 expression provided for predicting cancer recurrence (PPV) in HNSCC patients was measured by the ratio: PPVrelapse/HNSCC (83 months|S100A7)/PPVrelapse/HNSCC (83 months)  = 71.4/61.0; or for excluding (NPV) cancer recurrence in HNSCC patients was NPVrelapse/HNSCC (83 months|S100A7)/NPVrelapse/HNSCC (83 months)  = 57.1/39.0, as shown in Figure 3c and 3d respectively.