Phenotypic and genotypic features in the 6 patients carrying monoallelic MUTYH germline mutations show that monoallelic mutations have no association with being a carrier of synchronous polyps (p = 0.66) nor colorectal cancer (p = 0.79) and also no association between monoallelic mutations and family history (p = 0.38) (Table 6). Here, MUTYH is linked to colorectal cancer.