As many trauma patients are plagued by infections, researchers aimed to augment the host's inflammatory response by stimulating macrophages with glucan [29,30], activating monocytes with dextran [14], upregulating human leukocyte antigen (HLA)-DR expression with interferon (IFN)-γ [18,22,26,31], and providing immunoglobulins [20,32]. The gene discussed is IFNG; the disease is infection.