We found that when 10T1/2 cells, C3 H mouse embryonic mesenchymal stem cells (C3H/10T1/2) as characterized by us and others [22] (Fig. 1), were grown in different breast and pancreatic cancer cell-conditioned media for 2-4 days, the stem cells differentiate into pericytes with abnormally high expression of α-SMA along with Desmin (Fig. 2). Here, DES is linked to familial pancreatic carcinoma.