VEGFA and melanoma: Extending this analysis to all cell lines considered here, we also found that the amount of VEGF-A in the growth medium of the metastatic melanoma cells (49.2 ± 83.7 pg/ml) resulted significantly higher (p = 2.9 × 10-11) than that found in the primary melanoma cells (0.5 ± 0.2 pg/ml).