This study includes an extensive genetic survey in order to identify the molecular cause in 91 LCA probands mainly of Belgian origin, using LCA chip analysis for 8 to 13 genes and subsequent sequencing of the following genes: CEP290 (MIM# 610142), CRB1 (MIM# 604210), RPE65 (MIM# 180069), GUCY2D (MIM# 600179), AIPL1 (MIM# 604392) and CRX (MIM# 602225). Here, AIPL1 is linked to Leber congenital amaurosis.