Indeed, the BMP pathway may be involved in modulating the effect of Msx2 expression in breast cancer: analysis of BMP4 expression in 295 tumours from a transcriptomic dataset revealed that Msx2 is associated with high levels of BMP4 in breast tumours, and BMP4 itself was associated with improved patient outcome within this dataset. The gene discussed is MSX2; the disease is breast neoplasm.