NAT2 and urinary bladder cancer: We included 680 cases (of 1,219 in the full study) and 714 controls (of 1,271), and associations between bladder cancer and cigarette smoking, long-term exposure to THMs, and the main effects of NAT2 and GSTM1 (Garcia-Closas et al. 2005; Samanic et al. 2006; Villanueva et al. 2007) were comparable with those estimated for the full study population, suggesting that this subgroup is comparable with the full set of patients recruited to the study.