FCGR3A and melanoma: In the B16 metastatic mouse melanoma model FcγRI [34] and FcγRIV(CD16-2) [35], the equivalent of the human FcγRIIIA, were found to play a major role in the therapeutic effect of the TA99 mAb (a mAb anti-tyrosinase associated protein gp75) [36, 37].