ALB and aneurysm: Neither hypotonia (mean blood pressure < 65 mmHg) nor hypoxia (SpO2 < 90%), hyperthermia (>38°C), increased intracranial pressure (ICP > 20 mmHg), treatment with mannitol, increased cerebral blood flow velocity (>80 cm/s), or treatment modalities as aneurysm surgery or coiling, change of ventricular drainage, shunt implantation or tracheotomy did affect the passage of S100B or albumin through the blood-CSF barrier (P = .591).