As seen in the present study, the mean blood glucose concentration was increased in group B compared to group A. With the development of visceral obesity, the high circulating FFA leads to IR that promotes a dual effect to enhance hyperglycaemia by (i) down-regulating the insulin-sensitive glucose transporter 4 (GLUT4) via the Randle cycle and hence promotes an accumulation of glucose in the circulation and (ii) stimulating hepatic gluconeogenesis by antagonizing the action of insulin in the liver (hepatic IR) [8]. Here, SLC2A4 is linked to Hyperglycemia.