These analyses indicate that ERBB3 mRNA levels are significantly lower (p = 1.1×10−9 and 1.4×10−6, respectively) for the minor allele homozygotes (susceptible genotype) at rs2292239 and rs4759228 (Figure 2b), suggesting that reduced ERBB3 expression is associated with genotypes that confer increased risk for T1D. The gene discussed is ERBB3; the disease is type 1 diabetes mellitus.