Interestingly, the predictive targets of miR-152-p includes mitogen-activated protein kinase kinases MAP3K11 and MAP2K4, which activate the mitogen-activated protein kinase pathway implicated in the development and progression of many human cancers and the oncogene erbb4 and the cell adhesion protein 4 CADM4 involved in cell-cell adhesion. This evidence concerns the gene MAP2K4 and cancer.