Common canonical pathways in both time points include molecular mechanism of cancer, glioma signaling, hepatocyte growth factor (HGF) signaling, cell cycle regulation by B-cell translocation gene (BTG) family of proteins, P53 signaling, cell cycle: G2/M DNA damage checkpoint regulation, cell cycle: G1/S checkpoint regulation, ataxia telangiectasia mutated protein (ATM) signaling, ephrine receptor signaling, and virus entry via endocytic pathways. The gene discussed is TP53; the disease is glioma.