While mechanisms of transport modulation have been described previously, as in the indirect consequences of Ras, Rho, and Rab small GTPases regulation [87], its effect on viral infections and global cell biology remain unclear except for a recent report describing the interaction of myxoma poxvirus protein M11L with mitochondrial permeability transition pore and its role in delaying apoptosis in host cells [88]. The gene discussed is RHO; the disease is viral infectious disease.