Vionnet et al. have selected and studied 14 candidate genes including AGTR1, PTX3, IL12A, SLC2A2, TNFSF10, ECE2, THPO, EHHADH, HRG, KNG1, AdipoQ, SST, PPP1R2 and APOD from chromosome 3q24-29 and found that the AdipoQ promoter polymorphism rs17300539 is associated with DN in T1DM patients in Danish, but not in French and Finnish populations [14]. This evidence concerns the gene KNG1 and type 1 diabetes mellitus.