C2 and stroke disorder: There was some evidence (P = 0.03) for a difference between CHD cases and controls for a cytokine activity pathway (CCL5, C5, PF4, and CCL16), and some (P = 0.04) for an acute inflammatory response pathway (ORM1, ORM2, C2, CFHR1, MBL2, AHSG), whereas there was no evidence of corresponding differences between stroke cases and controls.