Cocktail 1 was designed as in a previous reported cocktail [21], where the combination of poly I:C, IFNα, IFNγ, TNFγ and IL-1β showed very potent IL-12p70 stimulating properties compared to the standard DC cocktail used for DC based cancer vaccines, containing IL-6, TNFα, IL-1β and PGE2. This evidence concerns the gene TNF and cancer.