To this end, the cocktails mimicking the early phases of Crohns disease are cocktails 1, 2, 4 and 5, since they induce key factors like TNFα, IL-6, IL-12p70, CCL2, 4, 8, CXCL1-3 and upon T-cell co-culture also IFNγ. The gene discussed is TNF; the disease is Crohn disease.