Similarly, the pathogenesis of psoriasis involves key Th1 and Th17 inducing cytokines like TNFα, IL-1β, IL-2, IL-6, IL-10, IL-12p70, IL-23, CCL2, 3, 4, 5, 20, CXCL1, 8, 9 and 10, many of which are induced by cocktail treated DCs. The gene discussed is TNF; the disease is psoriasis.