Table 3 shows the adjusted ORs of metabolic syndrome associated with a 1-SD increase in ln hs-CRP stratified by the status of insulin resistance, obesity, microalbuminuria, cardiovascular risk, and arteriosclerosis for men and women in order to examine the gender difference in the association of metabolic syndrome with hs-CRP according to the status of the above cardiovascular factors. This evidence concerns the gene CRP and obesity due to melanocortin 4 receptor deficiency.