For example, tunicamycin treatment of neuroblastoma cells [34] or expression of a retroviral protein in astrocytes, which induces ER stress [35], did not cause an upregulation of Erdj4, P58IPK , Erdj3, or Fkbp11. Importantly, all of these genes have been shown to be induced by ER stress caused by prolonged palmitate exposure in cultured mouse MIN6 cells [36]. This evidence concerns the gene DNAJB11 and neuroblastoma.